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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK1
All Species:
12.73
Human Site:
T692
Identified Species:
23.33
UniProt:
Q96PY6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PY6
NP_036356.1
1258
142828
T692
V
D
S
S
L
T
D
T
R
E
T
S
E
E
M
Chimpanzee
Pan troglodytes
XP_001153129
1258
142786
T692
V
D
S
S
L
T
D
T
R
E
T
S
E
E
M
Rhesus Macaque
Macaca mulatta
XP_001082793
1258
142958
I692
V
D
S
S
L
T
D
I
R
E
I
S
E
E
M
Dog
Lupus familis
XP_543184
1286
146207
T720
M
D
R
S
L
S
D
T
Q
E
T
S
E
D
M
Cat
Felis silvestris
Mouse
Mus musculus
P51954
1203
136672
T646
L
D
G
S
L
T
D
T
Q
E
E
E
M
E
K
Rat
Rattus norvegicus
NP_001099552
648
74414
D121
L
A
L
K
H
V
H
D
R
K
I
L
H
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
G337
K
M
W
N
S
P
G
G
A
Q
Q
P
I
S
V
Chicken
Gallus gallus
XP_420401
1281
145243
A706
V
D
G
N
V
T
A
A
Q
E
V
K
E
E
I
Frog
Xenopus laevis
Q7ZZC8
944
104521
S417
V
Q
K
V
S
C
G
S
D
F
T
V
C
I
T
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
I170
V
V
G
T
P
C
Y
I
S
P
E
L
C
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782796
1091
120115
D564
R
N
K
L
K
D
D
D
P
Q
I
S
A
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
I79
E
K
G
C
Y
V
C
I
I
I
G
Y
C
K
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
K331
L
S
A
L
E
T
E
K
S
S
I
R
A
E
I
Conservation
Percent
Protein Identity:
100
99.6
97.5
85
N.A.
79.2
45.9
N.A.
30.2
66.2
22.4
22.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
99.7
98.4
90.8
N.A.
85.6
48.5
N.A.
44.3
78
39.2
34.4
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
100
100
86.6
66.6
N.A.
53.3
6.6
N.A.
0
40
13.3
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
86.6
93.3
N.A.
66.6
20
N.A.
20
66.6
20
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
35.1
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
8
8
8
0
0
0
16
0
0
% A
% Cys:
0
0
0
8
0
16
8
0
0
0
0
0
24
0
0
% C
% Asp:
0
47
0
0
0
8
47
16
8
0
0
0
0
8
8
% D
% Glu:
8
0
0
0
8
0
8
0
0
47
16
8
39
62
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
31
0
0
0
16
8
0
0
8
0
0
0
16
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
24
8
8
31
0
8
8
16
% I
% Lys:
8
8
16
8
8
0
0
8
0
8
0
8
0
8
8
% K
% Leu:
24
0
8
16
39
0
0
0
0
0
0
16
0
0
0
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
31
% M
% Asn:
0
8
0
16
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
8
0
0
8
8
0
8
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
24
16
8
0
0
0
0
% Q
% Arg:
8
0
8
0
0
0
0
0
31
0
0
8
0
8
0
% R
% Ser:
0
8
24
39
16
8
0
8
16
8
0
39
0
8
0
% S
% Thr:
0
0
0
8
0
47
0
31
0
0
31
0
0
0
8
% T
% Val:
47
8
0
8
8
16
0
0
0
0
8
8
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _